Abstract:

Relationship between central lymph node ratio and the lateral lymph node metastasis in papillary thyroid microcarcinoma        GUO Kai, GUAN Qing, LI Duan-shu, et al. Department of Head and Neck Surgery, Fudan University Shanghai Cancer Center; Department of Oncology, Fudan University Shanghai Medical College, Shanghai 200032, China
Corresponding author: WANG Zhuo-ying, E-mail:zhuoyingwang@hotmail.com
Guo Kai and Guan Qing contributed equally to this work
Abstract    Objective    To explore the relationship between cLNR (Central Lymph Node Ratio) and the LLNM (Lateral Lymph Node Metastasis) in papillary thyroid microcarcinoma. Methods    This study retrospectively examined 859 patients with PTMC (Papillary Thyroid Microcarcinoma) in our hospital from Jan 2006 to Dec 2014.We analyzed the relationship between cLNR and LLNM/recurrence. Results    In the patients with suspected positive lateral cervical lymph node metastasis (cN1b+), we detected significant association between cLNR stratification, positive lymph node numbers and LLNM. Otherwise, there’s no significant difference between cLNR and recurrence in the patients with cN1b- disease, but lateral cervical recurrence obviously increased when positive number of central lymph node more than 3. Conclusion    There existed certain correlation between cLNR, metastatic numbers and LLNM.

Key words: Papillary thyroid microcarcinoma, Central lymph node ratio, Cervical lymph node metastasis, Recurrence

摘要：

目的    探讨甲状腺乳头状微小癌中央区淋巴结转移率（cLNR）与侧颈淋巴结转移的关系。方法    回顾性分析复旦大学附属肿瘤医院头颈外科2006年1月至2013年12月初治的859例甲状腺乳头状微小癌病人临床资料，研究其cLNR与侧颈淋巴结转移和复发的关系。结果    对于临床发现侧颈淋巴结转移者（cN1b+）病人，cLNR高低和转移个数与侧颈淋巴结转移关系密切；而对于临床未发现侧颈淋巴结转移者（cN1b-），cLNR的高低与侧颈复发差异无统计学意义，但中央区转移淋巴结>3个时，侧颈淋巴结复发率明显增高。结论    甲状腺乳头状微小癌cLNR及转移个数与侧颈淋巴结是否发生转移有一定的相关性。

关键词: 甲状腺乳头状微小癌, 中央区淋巴结转移率, 颈淋巴结转移复发