Abstract: Recurrence of early gastric cancer: Risk Factors and Patterns        WANG Xue-fei, SUN Yi-hong. Gastric Cancer Center/Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China. 
Corresponding author: SUN Yi-hong, E-mail: sun.yihong@zs-hospital.sh.cn
Abstract    Postoperative recurrence is the major factor to limit the prognosis of patients with early gastric cancer (EGC). The etiology of EGC recurrence is still under the scope of the tumorigenesis of malignancies. The heterogeneity of EGC calls for better risk stratification of recurrence in ECG patients. Standardization of endoscopic treatments is the key to reducing postoperative recurrence of EGC. Here, we reviewed the common recurrence patterns of EGC, including in-situ recurrence, recurrence of the remnant stomach, regional recurrence, and distant metastasis. The precise prevention and treatment of EGC should be based on a deeper insight into the etiology, risk factors, pathological heterogeneity, and clinical characteristics of EGC.

Key words: early gastric cancer, recurrence, metastasis

摘要： 早期胃癌病人整体预后良好，术后复发转移是限制其疗效进一步提高的根本原因。恶性肿瘤的病因仍然是影响早期胃癌复发的主要原因；胃癌的组织病理学类型及肿瘤生物学行为的异质性决定了早期胃癌转移复发的危险度；内镜微创治疗的规范程度和技术水平也是影响早期胃癌术后复发的重要因素。早期胃癌的复发模式主要包括原位复发、残胃复发、区域复发和远处转移等。临床上应详细分析早期胃癌的临床病理特征，深入了解其术后复发的高危因素、可能机制和临床特点，选择规范合理的治疗技术。随着肿瘤复发转移理论的完善和新检测技术开发，早期胃癌复发转移的精准预防和干预是未来最有可能取得突破性进展的重要方向之一。

关键词: 早期胃癌, 复发, 转移