Abstract: Progression of sentinel lymph node in early gastric cancer        HUANG Wen-bai，LIANG Han. Department of Gastric Cancer，Tianjin Medical University Cancer Institute and Hospital；National Clinical Research Center of Cancer；Key Laboratory of Cancer Prevention and Therapy，Tianjin 300060，China
Corresponding author：LIANG Han，E-mail：tjlianghan@126.com
Abstract    Endoscopic or laparoscopic gastrectomy are the main treatments of early gastric cancer. The combination of sentinel lymph node（SLN） tracing technique is considered as a means to preserve gastric function and improve the quality of life of patients under the premise of ensuring radical resection of gastric cancer. However，sentinel lymph node navigation surgery for early gastric cancer has been controversial due to the particularity of gastric lymph node metastasis pathway. With the concept of lymphatic basin dissection，sentinel node navigation surgery（SNNS） for early gastric cancer has been guaranteed.  With the publication of SENORITA study，the safety and efficacy of SNNS for early gastric cancer have been further confirmed. Lymphatic basin dissection combined with laparoscopic/endoscopic surgery may become a new treatment for early gastric cancer.

Key words: early gastric cancer, sentinel lymph node, function-preserving gastrectomy, endoscope, laparoscope

摘要： 内镜切除和腹腔镜手术是早期胃癌治疗的主要手段，结合前哨淋巴结（SLN）示踪技术被认为是能在保证肿瘤根治前提下达到保留胃功能、改善病人生活质量的手段。但由于胃癌淋巴结转移途径的特殊性，早期胃癌SLN导航手术（SNNS）一直存在争议。随着SLN引流区概念的提出，早期胃癌SNNS的根治性得到更好的保证。尤其是SENORITA研究结果的发表，早期胃癌SNNS的安全性和有效性得到进一步证实。SLN引流区清扫联合腹腔镜或内镜手术将成为有效的早期胃癌治疗手段。

关键词: 早期胃癌, 前哨淋巴结, 保留功能的胃切除术, 内镜, 腹腔镜