Abstract: Risk factors and management of postoperative recurrence of thyroid cancer in children and adolescents                    FAN You-ben, DENG Xian-zhao, WU Bo. Department of General Surgery, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Thyroid Disease Diagnosis and Treatment Center of Shanghai Jiaotong University, Shanghai 200233,China 
Corresponding author：FAN You-ben, E-mail:fanyouben2006@ 163.com
Abstract    Differentiated thyroid cancer（DTC）is most common thyroid malignance in children and adolescents.Thyroid cancer in children and adolescents is often accompanied by local invasion，regional lymph node metastasis and even distant metastasis when being detected，which can result in a high recurrence rate.Nonstandard clearance of gland and lymph node may also be a high risk factor of postoperative recurrence.Children and adolescents with DTC recurrence need to be carefully operated again by throid specialists.Postoperative 131I treatment , reasonable endocrine inhibition therapy and long-term follow-up must be performed after operation.

Key words: thyroid cancer, children, adolescents, recurrence, risk factors, therapy

摘要： 儿童及青少年甲状腺癌主要是分化型甲状腺癌，发现时易伴有局部侵犯、区域淋巴结转移甚至远处转移，及过多的放射性暴露和遗传因素，是术后复发率较高的重要因素。未行全甲状腺切除术及颈淋巴结清扫范围不够也是复发的高危因素。儿童及青少年甲状腺癌术后复发须及时仔细彻底再次手术，减少手术并发症，术后行适度的内分泌抑制治疗和131I治疗并长期随访。

关键词: 甲状腺癌, 儿童, 青少年, 复发, 危险因素, 处理