Abstract: Advances in preoperative treatment of hepatocellular carcinoma        SUN Hui-chuan.  Department of Liver Surgery, Zhongshan Hospital Affiliated to Fudan University, Shanghai 200032, China
Abstract    Among new patients with liver cancer in China，60%～70% are already in the middle and advanced stages when they are first diagnosed, and have lost the chance of a radical cure. Improving the early diagnosis rate and early treatment are the most effective way to improve the survival rate at present; but for a large number of patients with advanced stage, more effective treatment options are needed. With the gradual progress of systemic treatment protocols, patients at advanced stage have ushered in an opportunity to the enhancement of therapeutic effect, and systemic treatment combined with local treatment or surgical treatment may help to further improve the curative effect of patients with advanced liver cancer. Chinese scholars have achieved preliminary results in the exploration of this field. More high-quality studies will be published in the coming years, hopefully confirming the value of such combined treatment strategies.

Key words: hepatocellular carcinoma, advanced liver cancer, systemic therapy, survival rate

摘要： 我国肝细胞癌（简称肝癌）新发病人中，60%～70%首诊时已处于中晚期，失去了根治的机会。提高肝癌的早期诊断率并及早进行治疗是目前提高生存率最有效的手段；但对于大量的中晚期肝癌病人，需要提供更为有效的治疗方案。随着系统治疗方案的逐渐进步以及疗效的提高，中晚期肝癌病人迎来了一个疗效提升的时机，而系统治疗联合局部治疗、外科治疗，可能有助于进一步提高中晚期肝癌病人的疗效。我国学者在这个领域的探索已获得初步的成果。未来几年将有更多高质量研究发表，有望确认这类联合治疗策略的价值。

关键词: 肝细胞癌, 中晚期肝癌, 系统治疗, 生存率