Abstract:

Interpretation of international consensus on definition and criteria of borderline resectable pancreatic ductal adenocarcinoma 2017        SUN Bei, YANG Wen-bo, HU Ji-sheng. Department of Pancreatic and Biliary Surgery, the First Affiliated Hospital of Harbin Medical University, Harbin 150001,China
Corresponding author：Sun Bei,E-mail：sunbei70@tom.com
Abstract Borderline resectable pancreatic ductal adenocarcinoma(BR-PDAC), characterized by high risk for positive margin with resection, high post-operative recurrence rate and poor prognosis, is a special kind of pancreatic ductal adenocarcinoma between resectable and nonresectable type. Neoadjuvant multimodality therapy is recommended as the first approach in recent years. To address related issues and seek an international consensus on BR-PDAC, a symposium was arranged during the 20th meeting of the International Association of Pancreatology (IAP) held in Sendai, Japan, in 2016. Finally, the definition of BR-PDAC is based on three distinct dimensions: anatomical (A), biological (B) and conditional (C), and requires one or more positive dimensions(e.g. A, B, C, AB, AC, BC or ABC). The present consensus acknowledges that resectability is not just determined by anatomic relationship between the tumor and vessels, but that biological and conditional factors are also important.

Key words: pancreatic ductal adenocarcinoma, borderline resectable, consensus

摘要：

可能切除胰腺导管腺癌（BR-PDAC）是介于可切除与不可切除胰腺导管腺癌之间的类型，因其术后切缘阳性可能性大，易复发，预后较差，故近年来多建议先行新辅助综合治疗。2016年在日本仙台召开的第20届国际胰腺病学会会议期间，部分与会专家针对BR-PDAC的相关问题进行了讨论，寻求新的共识，最终通过解剖学anatomical（A）、生物学biological（B）和条件性conditional（C）3个方面进行定义，当满足其中一方面或以上的标准时即可定义为BR-PDAC（如A、B、C、AB、AC、BC或ABC）。该共识强调可切除性不仅取决于肿瘤与血管的解剖学关系，而且生物学因素和条件性因素同样至关重要。

关键词: 胰腺导管腺癌, 可能切除, 共识