Abstract:

Consensus and controversy on multimodal therapy for hepatocellular carcinoma        LI Xiang-cheng，LI Chang-xian，ZHANG Jia-wei，et al. Liver Transplantation Center，the First Affiliated Hospital of Nanjing Medical University，Nanjing 210029，China
Corresponding auhor：LI Xiang-cheng，E-mail：drxcli@njmu.edu.cn
Abstract    With the development of medical technology，the treatment of hepatocellular carcinoma (HCC) has developed into a multidisciplinary and multimodal treatment model. At present，there are many treatments for HCC，including surgical resection, liver transplantation，ablation，transarterial chemoembolization，radioembolization，molecular targeted therapy, chemotherapy，immunotherapy and so on. To improve the overall curative effect of HCC，the treatment plan should be formulated according to different individuals by using multidisciplinary advantages. At present，surgery is still the best radical treatment for the patients with resectable HCC. Comprehensive treatment can be an important supplement to surgical treatment, which increase the chance of surgical resection and reduce postoperative recurrence and metastasis，and provide a good treatment opportunity for advanced HCC patients，and prolong the survival of patients.

Key words: hepatocellular carcinoma, multimodal treatment, anatomic resection, non-natomic resection, liver transplantation

摘要：

随着医疗技术的进步，肝细胞肝癌的治疗已经进入多学科、多模式共存阶段。针对肝癌的治疗方法有很多种，包括手术切除、肝移植、动脉化疗栓塞、消融、分子靶向药物治疗、放疗、化疗、免疫治疗等。应根据不同个体制定相应治疗方案，利用多学科优势，提高肝癌病人的整体疗效。目前，手术仍然是肝癌最好的根治性治疗手段，可手术切除病人应尽量争取手术治疗。综合治疗可作为手术治疗的重要补充，增加外科手术切除机会，减少术后复发转移，为晚期肝细胞肝癌病人提供良好的治疗机会，延长病人的生存期。

关键词: 肝细胞性肝癌, 多模式治疗, 解剖性肝切除, 非解剖性肝切除, 肝移植