Abstract:

Elevated incidence of recurrent pregnancy loss is found in the women with metabolic syndrome.The mechanism may be in association with prothrombotic state，poor endometrial decidualization，luteal phase deficiency，and maternal-fetal interface immune dysfunction.Lifestyle modification，weight reduction，blood glucose control，luteal phase support，and anti-coagulation may improve future pregnancy outcomes.

Key words: metabolic syndrome, recurrent pregnancy loss, polycystic ovarian syndrome, obesity, insulin resistance

摘要：

代谢综合征患者发生复发性流产的概率升高，可能与血栓前状态、子宫内膜蜕膜化不良、卵子质量差、母胎界面免疫紊乱等机制有关，通过生活方法干预、减重、控制血糖、加强黄体支持以及抗凝可望改善再次妊娠结局。

关键词: 代谢综合征, 复发性流产, 多囊卵巢综合征, 肥胖, 胰岛素抵抗