Abstract: Necrotizing enterocolitis totalis （NEC-T） is one of the most severe forms of necrotizing enterocolitis，with rapid progression，a high risk of poor prognosis，and a lack of universally accepted treatment strategies. This article summarized the risk factors，treatment decision，prognosis and possible ethical issues in the management of NEC-T，and presented some difficulties and dilemma in the course of clinical diagnosis and treatment.

Key words: necrotizing enterocolitis, totalis, neonate

摘要： 全肠道坏死性小肠结肠炎（necrotizing enteroco-litis totalis，NEC-T）是坏死性小肠结肠炎（NEC）中最严重的类型，病情发展迅速，预后不良风险较高，且目前缺少普遍认可的诊疗策略。该文就NEC-T的危险因素、治疗决策及预后、治疗过程中可能面临的伦理问题等进行概述，并阐述临床诊治过程中的难题与困境。

关键词: 坏死性小肠结肠炎, 全肠道坏死性, 新生儿