Abstract: Necrotizing enterocolitis （NEC） is a serious intestinal inflammatory disease in the neonatal period，which can lead to the death of newborns，premature infants especially. Serum amyloid A protein （SAA） is an acute phase reactive protein secreted by liver. The content of SAA increases sharply when the body has an acute phase response. As a pro-inflammatory factor，it accelerates the body's inflammatory reaction，and has important value for the early recognition，diagnosis and assessment of NEC.

Key words: serum amyloid A protein, neonatal necrotizing enterocolitis, predictor

摘要： 坏死性小肠结肠炎（necrotizing enterocolitis，NEC）是新生儿期严重的肠道炎症性疾病，可导致新生儿尤其是早产儿死亡。血清淀粉样蛋白A（serum amyloid A protein，SAA）是一种由肝脏分泌的急性时相反应性蛋白，在机体发生急性时相反应时含量急剧升高，作为促炎因子加速机体的炎症反应，对新生儿NEC的早期识别、诊断与评估具有重要价值。

关键词: 血清淀粉样蛋白A, 新生儿坏死性小肠结肠炎, 预测因子