Chinese Journal of Practical Pediatrics ›› 2024, Vol. 39 ›› Issue (2): 94-98.DOI: 10.19538/j.ek2024020604

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Progress in the diagnosis and treatment of pulmonary mycormycosis in children

  

  1. Department of Respiratory Medicine,Wuhan Children's Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan  430016,China
  • Online:2024-02-06 Published:2024-02-26

儿童肺部毛霉菌感染的诊治进展

  

  1. 华中科技大学同济医学院附属武汉儿童医院呼吸科,湖北  武汉  430016 
  • 通讯作者: 陆小霞,电子信箱:lusi74@163.com
  • 基金资助:
    湖北省卫生健康委科研项目(WJ2021M262)

Abstract: Mucormycosis is an infection caused by members of the order Mucorales that can involve many organs,including the skin,paranasal sinuses,orbits,brain,lungs,and gastrointestinal tract. Pulmonary mucormycosis is a very common forms which mainly occurs in immunocom-promised patients. The disease tends to progress rapidly with a high mortality rate.Early recognition of infection and active treatment are of great significance.This review covers the following aspects to provide a reference for the diagnosis and treatment of child pulmonary mucormycosis:epidemiology,pathogenesis,clinical presentation,imaging manifestations,diagnosis and treatment.

Key words: mucormycosis, child, epidemiology, diagnosis, treatment

摘要: 毛霉菌感染是由毛霉目真菌感染所致的疾病,可累及皮肤、鼻-眶-脑、肺、胃肠道等多个部位。肺毛霉病是其较为常见的类型,好发于免疫功能低下患者。其病情进展快,病死率高。因此早期诊断和积极治疗极为关键。该文介绍肺毛霉病的流行病学、致病机制、临床表现、影像学表现、诊断及治疗,以期为儿童肺毛霉病的诊治提供参考。

关键词: 毛霉菌病, 儿童, 流行病学, 诊断, 治疗