Abstract: Airway mucociliary apparatus is the first line of defense of airway immunity. The dynamic equilibrium between mucus secretion and clearance is the guarantee for maintaining the normal physiological function of airway. Excessive mucus secretion， accumulation and/or increase in viscosity in the airway may affect the development and prognosis of the disease， resulting in recurrent respiratory tract infections， gas exchange disorders， and even changes in airway structure in severe cases. It is important to pay attention to mucinous obstructive pulmonary disease caused by excessive airway mucus secretion and provide effective treatment and management in order to maintain normal airway function and achieve pulmonary rehabilitation.

Key words: child, airway diseases, hypersecretion of mucus, management

摘要： 气道黏液纤毛装置是构成呼吸道免疫的第一道防线，其中黏液分泌与清除的动态平衡是维持气道正常生理功能的保障。气道黏液分泌过多、积聚和（或）黏液黏度的增加均可影响疾病发展和预后，造成呼吸道反复感染、气体交换障碍，严重者可导致气道结构改变。重视气道黏液高分泌引起的黏液阻塞性肺疾病，并给予有效治疗和管理，对维持气道正常功能及肺康复均有重要意义。

关键词: 儿童, 气道疾病, 黏液高分泌, 管理