Chinese Journal of Practical Pediatrics ›› 2023, Vol. 38 ›› Issue (9): 654-664.DOI: 10.19538/j.ek2023090602

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Expert consensus on risk stratification and application of cardiac magnetic resonance in children with myocarditis

  

  • Online:2023-09-06 Published:2023-09-22

心脏磁共振指导儿童心肌炎的危险分层和应用专家共识

  

  1. 执    笔:杨    曦,刘桂英,赵    蕾,于宪一,陈  笋,金红芳,石    琳
    制定专家(按单位首字汉语拼音顺序排序):北京大学第一医院(金红芳,张春雨);首都医科大学附属北京安贞医院(刘桂英,杨    曦,李    佳,苏    瑛,赵    蕾,王霄芳,杜    靖,李晓明,蒲俊舟);首都医科大学附属北京友谊医院(崔  红);首都医科大学附属北京朝阳医院(秦选光);首都医科大学附属北京儿童医院(唐浩勋,曹永丽,阴    捷);首都儿科研究所附属儿童医院(石    琳,李晓惠);广东省人民医院(谢育梅);河北省人民医院(杨艳章);华中科技大学同济医学院附属协和医院(彭    华);吉林大学第一医院(孙景辉,王    玥);暨南大学附属第一医院(杨德光);空军军医大学第二附属医院(杨    勇);空军军医大学第一附属医院(朱晓丽);内蒙古医科大学附属医院(李    鹏,张晓蒙);上海交通大学医学院附属新华医院(陈    笋,郁    怡);山西省运城市中心医院(赵旭晶);天津医科大学总医院(孙永梅);温州医科大学附属育英儿童医院(吴蓉洲);云南省曲靖市第一人民医院(崔亚梅);浙江大学医学院附属儿童医院(傅松龄);中国医科大学附属盛京医院(于宪一);中日友好医院(张    琪,张    静);中山大学附属第一医院(覃有振);中南大学湘雅三医院(陈志衡);中国人民解放军总医院第四医学中心(王秋霜)
  • 通讯作者: 刘桂英,电子信箱:liugvying@126.com;于宪一,电子信箱:yuxy@sj-hospital.org
  • 基金资助:
    国家重大科学仪器设备开发专项(2013YQ03092306);北京市科技计划项目(Z111107067311030);北京市临床重点专科建设项目(2-1-2-18-300)

Abstract: Myocarditis refers to the inflammatory injury of myocardial tissue caused by various reasons. The clinical manifestations of myocarditis are nonspecific and vary greatly. At present, the diagnosis of myocarditis mainly depends on auxiliary examinations, such as electrocardiogram, serological indicators, and echocardiography, but these examinations are limited in sensitivity and specificity, and have limited value in risk stratification. Cardiac magnetic resonance imaging (CMR) can detect pathological changes in the myocardium early, and has become the gold standard for evaluating such changes as myocardial congestion, necrosis, fibrous scars, and myocardial activity. It is strongly associated with adverse cardiovascular events, including cardiac function deterioration, heart failure, arrhythmia, cardiac arrest, and even cardiovascular death or all cause death. Therefore, rational application of CMR is helpful to the risk stratification of children with myocarditis.

Key words: child, myocarditis, cardiac magnetic resonance, risk stratification, expert consensus

摘要: 心肌炎是指各种原因导致的心肌组织的炎性损伤,病因较多,感染是最主要的病因。心肌炎临床表现无特异性,且变化较大。目前,心肌炎诊断主要依赖心电图、血清学指标、超声心动图等辅助检查,但这些检查灵敏度有限,特异性低,对儿童心肌炎的危险分层价值有限。心脏磁共振成像(CMR)能够早期发现心肌病理改变,已成为评价心肌充血渗出、坏死、纤维瘢痕和心肌活性等改变的金标准,CMR表现与心功能恶化、心力衰竭、心律失常、心脏骤停,甚至心血管死亡或全因死亡等不良心血管事件显著相关。因此,合理应用CMR有助于心肌炎患儿的危险分层。

关键词: 儿童, 心肌炎, 心脏磁共振, 危险分层, 专家共识