Abstract:

Diffuse panbronchiolitis（DPB），an idiopathic inflammatory disease，is characterized by chronic respiratory bronchioles of the bilateral lung. The etiology and pathogenesis of DPB is unknown. The main etiology is now believed to be related to gene and infection. Pathological examination is the gold standard for DPB diagnosis. Low-dose and long-term treatment with macrolides has been shown to significantly improve the prognosis of DPB patients.

Key words: diffuse panbronchiolitis, clinical manifestation, diagnosis, treatment

摘要：

弥漫性泛细支气管炎（DPB）是一种以弥漫存在于两肺细支气管及呼吸性细支气管区域并累及管壁全层的慢性炎症为特征的疾病。DPB病因及发病机制未明，目前认为主要与基因、感染等因素有关。病理检查是DPB确诊的金标准。尽早诊断，应用大环内酯类药物小剂量长期治疗，可改善预后。

关键词: 弥漫性泛细支气管炎, 临床表现, 诊断, 治疗