Abstract: Atopic dermatitis is a common chronic，recurrent，inflammatory，pruritus，and refractory skin disease in children. The etiology and pathogenesis of AD are complex. At present，there’re four critical factors related to it，including genetic and acquired skin barrier dysfunction，immune abnormalities，flora microecological disorder，environment，and so on. The clinical manifestation of AD is pleomorphic. The typical rash morphology and distribution sites of different ages are different and could also be accompanied by various atypical rashes. Its diagnosis still depends on clinical manifestations. Although the exact causes of AD are still unclear，significant progress has been made in the roles of different causes in AD，which provides theoretical support for the clinical application of new treatment schemes. Here，we mainly introduce the clinical manifestations，diagnosis，and the progress of nonsystematic treatment for AD children.

Key words: atopic dermatitis, child, diagnosis, nonsystematic treatment

摘要： 特应性皮炎(atopic dermatitis，AD)是儿童常见的慢性、复发性、炎症性、瘙痒性、难治性皮肤疾病，儿童为AD易感人群。AD的病因及发病机制复杂，与遗传及获得性的皮肤屏障功能障碍、免疫异常、菌群微生态紊乱及环境等多种因素相关。AD的皮疹表现为多形性，不同年龄的典型皮疹形态及分布部位有所不同，还可伴有多种非典型皮疹，其诊断仍依靠临床表现。目前AD发病的确切因素尚不明确，但针对不同病因在AD中的作用机制的研究取得了较大进展，这为新治疗方案的临床应用提供了理论支持。该文主要介绍儿童AD的临床表现、诊断及非系统治疗的研究进展。

关键词: 特应性皮炎, 儿童, 诊断, 非系统治疗