Abstract:

Current status of surgical treatment in gastric cancer with para-aortic nodal metastases        HU Xiang. Department of General Surgery，the First Affiliated Hospital of Dalian Medical University，Dalian 116011，China
Abstract     Para-aortic lymph node metastasis（No.16a2，No.16b1）is a non-curative factors with stage Ⅳ gastric cancer. The prognosis is poor. The high-level evidence based medical clinical research（JCOG0405 trail） results proved that R0 resection can be performed by the technology of operation after systemic preoperative chemotherapy for the patients of stage Ⅳ gastric cancer with only one non-curative factor of para-aortic lymph node metastasis positive. And the satisfactory prognosis was achieved. In this regard，comprehensive treatment including surgical resection is the first choice and standard treatment for the stage Ⅳ gastric cancer with para-aortic lymph node metastasis. 

Key words: stage Ⅳ gastric cancer, chemotherapy, conversion therapy, para-aortic lymph node

摘要：

腹主动脉周围淋巴结（No.16a2、No.16b1）转移是胃癌的非治愈性因素，即属于Ⅳ期胃癌，其预后不良。近年，日本JCOG0405试验证明非治愈性因素仅为腹主动脉周围淋巴结转移阳性，系统化疗后行R0切除，病人能够获得良好的长期生存效果。因此，包含外科切除手术的综合治疗成为腹主动脉周围淋巴结转移胃癌的首选（即标准治疗）。

关键词: Ⅳ期胃癌, 化学疗法, 转化治疗, 腹主动脉周围淋巴结