Abstract: Focus and countermeasure of surgical treatment for young women with breast cancer        WU Ke-jin, CHEN Hong-liang. Department of Breast Surgery, Obstetrics & Gynecology Hospital of Fudan University, Shanghai 200011, China
Corresponding author:WU Ke-jin,E-mail：kejinwu@163.com
Abstract    Poor prognosis of young breast cancer patients is closely related to invasive biological characteristics, which is a major difficulty in clinical treatment. The choice of surgical treatment for young women with breast cancer requires comprehensive consideration of tumor biological characteristics, patient's own needs, social and family support factors and so on. Breast conserving surgery should be actively carried out for early-stage tumors. For tumors with late clinical stage, it is recommended to actively carry out neoadjuvant therapy according to molecular typing, or implement appropriate breast reconstruction technology. Clinicians should provide patients with more sufficient information and high-level evidence-based medical evidence, and encourage patients to actively participate in surgical decision-making.

Key words: young women, breast cancer, breast-conserving surgery, mastectomy, breast reconstruction, endoscopic assisted surgery, neoadjuvant chemotherapy

摘要： 年轻乳腺癌病人预后较差，与侵袭性生物学特征密切相关，是临床治疗的一大难点。年轻女性乳腺癌病人的外科手术抉择需要综合权衡肿瘤生物学特征、病人的自身需求、社会家庭支持因素等各个方面。对于早期肿瘤应当积极开展保乳手术，对于临床分期较晚的肿瘤，建议参照分子分型积极开展新辅助治疗，或者实施合适的乳房重建技术。临床医师应当为病人提供更加充分的信息与高级别的循证医学证据，鼓励病人积极参与外科手术决策的制定。

关键词: 年轻女性, 乳腺癌, 保乳手术, 乳房切除术, 乳房重建, 腔镜辅助手术, 新辅助化疗