Abstract:

Application value and controversy of laparoscopic surgery in gastric GIST        XU Ze-kuan, XU Hao, LI Feng-yuan. Department of General Surgery, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China
Corresponding author: XU Ze-kuan, E-mail：xuzekuan@njmu.edu.cn
Abstract    Gastrointestinal stromal tumor (GIST) has unique biological and clinical characteristics. Surgical treatment and molecular targeted therapy are the main means of gastric GIST. With the rapid development of laparoscopic technology in recent years, laparoscopic surgery for gastric GIST has gradually replaced the traditional open operation and has become a trend in the future. However, the laparoscopic treatment of gastric GIST for the size of gastric GIST and the special part of the stomach is still controversial. From the update of NCCN treatment guideline, the size limitation of laparoscopic treatment of gastric GIST can be broken. It depends on the location of tumor lesions, the professional level of doctors and the degree of cooperation of medical teams. For the special part of the gastric GIST, the surgeon can choose the operative method flexibly according to its particularity to achieve the purpose of complete resection of the tumor and preserve the function of the stomach.

Key words: gastrointestinal stromal tumor, stomach, laparoscope

摘要：

胃肠间质瘤（GIST）具有独特的生物学行为与临床特征。外科手术治疗和分子靶向治疗是胃GIST的主要手段。近年来随着腹腔镜技术的快速发展，胃GIST的腹腔镜手术治疗逐渐替代传统开放手术，并成为未来发展的趋势。但行腹腔镜手术治疗时，对于胃GIST的大小和特殊部位的胃GIST目前仍存在争议。从美国国家综合癌症网络（NCCN）治疗指南的更新中看出，对腹腔镜手术治疗胃GIST的大小限制是可以打破的，关键取决于肿瘤病变的部位、医生专业水平和医疗团队配合的程度。对于特殊部位的胃GIST，外科医生可根据其特殊性尝试灵活选择术式以达到完整切除肿瘤和保留胃功能的目的。

关键词: 胃肠间质瘤, 胃, 腹腔镜