Abstract:

Strategies of diagnosis and treatment of gastric cancer in the era of big data and precision medicine        JI Jia-fu, LI Zhe-min, XUE Kan, et al. Center of Gastrointestinal Tumors, Peking University School of Oncology, Beijing Cancer Hospital & Institute; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Beijing 100142, China
Corresponding author: JI Jia-fu, E-mail：jiafuji@hotmail.com
Abstract    The era of big data and precision medicine has brought new horizon for diagnosis and treatment of gastric cancer. The acquisition of clinical and personal biological data has made personalized treatment possible. Based on the precondition of precise diagnosis, patients with relatively early stage should avoid unnecessary injury, and patients with relatively late stage should be performed multi-disciplinary treatment according to indication for target therapy, chemotherapy and surgery accurately to improve the efficiency of treatment and overall survival. Through the establishing and exploring of the national data sharing and analysis platform, precision medicine program suitable for Chinese conditions should be proposed in the future.

Key words: gastric cancer, precision medicine, big data

摘要：

大数据和精准医疗时代对胃癌的诊治提出了新的要求。临床数据及个人分子生物学信息的获得使得个体化的精准医疗成为可能。在精准诊断的前提下，对病期偏早的胃癌病人，应减少不必要的治疗创伤;而对病期偏晚的胃癌病人，应采用多学科综合诊疗模式，精确靶向治疗、化疗、手术等治疗适应证，提高治疗有效率，改善病人生存质量。通过建立全国数据共享与分析平台，不断探索，结合我国国情提出适宜自身特点的精准医疗方案。

关键词: 胃癌, 精准医疗, 大数据