Abstract:

Rethinking the standardization and advances in diagnosis and treatment of colorectal liver metastases from ESMO Clinical Practice Guidelines for Metastatic Colorectal Cancer        YAO Hong-wei, XIU Dian-rong.   Department of General Surgery, Peking University Third Hospital, Beijing 100191, China
Corresponding author: XIU Dian-rong, E-mail: xiudianrong@medmail.com.cn
Abstract    Colorectal liver metastases (CLM) is the most common site of distant metastases and one of the most common leading causes in patients of colorectal cancer. In recent years, along with the updatingconcept of diagnosis and treatment, more and more patients of CLM received surgical treatment opportunities and improved survival. Based on evidence-based medicine, clinical practice guidelines for metastatic colorectal cancer was released by European Society  for Medical Oncology in 2014.Standardized strategy of diagnosis and treatment for CLM was recommended, which included diagnosis and treatment by multidisciplinary team, accurate evaluation of the resectability, active surgical resection, proper comprehensive treatment and personalized medicine for CLM.

Key words: colorectal liver metastases, multidisciplinary team, resectability, personalized treatment

摘要：

结直肠癌肝转移（CLM）是结直肠癌病人最为常见的远处转移部位以及最主要的死亡原因。近年来，随着诊治理念的更新，越来越多的CLM病人获得手术治疗的机会并且预后得以改善。基于循证医学的证据，2014年欧洲肿瘤内科学会（ESMO）发布了《ESMO转移性结直肠癌的诊断、治疗和随访临床实践指南》，推荐对CLM进行规范化诊断和治疗，这包括多学科团队协作诊治、准确评估CLM的可切除性、积极的手术治疗、恰当的综合治疗方案以及个体化的药物治疗。

关键词: 结直肠癌肝转移, 多学科团队, 可切除性, 个体化治疗