Abstract:

Objective:To summarize the experience of diagnosis of solid pseudopapillary tumor of pancreas (SPT). Methods:Clinical manifestations, laboratory examination, imageology, pathology of 24 patients with SPT admitted in general hospital of the People’ Liberation Army from February 2000 to March 2007 were retrospectively analyzed. Results:23 of 24 patients were female and the mean age was 244 years. Clinical presentation included a palpable abdominal mass in 5 patients, abdominal pain in 7 cases,diarrhea in 1 patient, nausea and abdominal distention in 2 cases.9 patients were asymptomatic.Tumor markers in all patients were negative.Abdominal imaging showed solid and solid cystic masses in pancreas or abdominal cavity.13 cases located in the head of pancreas,4 in the body of pancreas,7 in the tail of pancreas.2 cases received preoperative ultrasonic guidance biopsy and 6 underwent freezing pathology around surgery,1 case and 3 cases were diagnosed as SPT respectively. Conclusion:The correct diagnosis of SPT depends on comprehensive analysis of clinical feature,image and histopathologic characteristic.

Key words: pancreatic neoplasm, solid pseudopapillary tumor of pancreas

摘要：

目的:总结胰腺实性假乳头状瘤（SPT）的临床特征与诊断经验。方法:对2000年2月至2007年3月在中国人民解放军总医院经术后病理证实的24 例SPT的临床表现和实验室、影像学、术前及术中病理检查等资料进行回顾性分析。结果:女性23例，男性1例，平均年龄24.4岁。首诊临床表现为腹部肿物5例、腹痛7例、腹泻1例、恶心腹胀2例等，9例无任何临床症状。血清肿瘤标记物水平均正常。影像学检查均提示胰腺或腹腔内边界清楚的实性或囊实性占位病变，肿瘤位于胰头部13例，胰体部4例，胰尾7例，核磁共振（MRI）的诊断符合率（40.0%）要高于CT（16.7%）。术前2例行超声引导下肿瘤活组织检查，6例行术中快速冰冻病理检查，分别有1例和3例诊断为SPT。结论:SPT的正确诊断依赖于临床表现、影像学特征，尤其是病理学检查的综合分析。

关键词: 胰腺肿瘤, 实性假乳头状瘤