Abstract:

Clinical development of the perioperative iodide application in patients with hyperthyroidism        FU Yan-tao, SUN Hui. Department of Thyroid Surgery, China-Japan Union Hospital of Jilin University, Changchun 130033, China
Corresponding author: SUN Hui, E-mail：thyroidjl@163.com
Abstract    Iodide has been used as an adjuvant treatment in patients with hyperthyrodism planned for thyroidectomy for almost a century.Although the mechanism of application of iodide is still unclear and the use of methods is uniform，iodide has been shown to decrease thyroid hormone levels and reduce blood flow within the thyroid gland. Iodide could reduce complications and the mortality rate of thyroidectomy.Because of the advancement of disease awareness，the application of anti-thyroid drugs（ADT），the use of intraoperative energy devices，and the improvement of surgical techniques，the standard application of perioperative iodide is challenged and new preoperative preparation methods for hyperthyroidism has begun to emerge.

Key words: hyperthyroidism, 131I, preoperative preparation

摘要：

碘剂应用于甲状腺功能亢进（简称甲亢）的术前准备已有近100年历史，明显降低了甲亢手术死亡率。虽然碘剂的应用机制仍然不是十分清楚，使用方法不尽相同，但它能够降低甲状腺激素水平，减少甲状腺血流和术中出血，为手术的安全性提供了保障。随着对疾病认识的进步、抗甲状腺药物的应用、术中能量器械的使用、手术技术的提高，甲亢术前常规应用碘剂的方法受到质疑，新的术前准备方法开始出现。

关键词: 甲状腺功能亢进, 碘131, 术前准备