Abstract:

Outlines and summarization of 2015 ESMO Clinical Practice Guideline for Diagnosis, Treatment and Follow-up of Primary Breast Cancer        ZHENG Xin-yu,WANG Qiu-li. Department of Breast Surgery, the First Hospital of China Medical University, Shenyang 110001, China
Corresponding author:ZHENG Xin-yu, E-mail: xyzheng126@126.com
Abstract    Breast cancer is the most common malignancy in women in China and its incidence is increasing fast recently. The overall management of primary breast cancer includes the treatment of local disease with surgery, radiation therapy, or both, and the adjuvant systemic treatment with chemotherapy, endocrine therapy, biologic therapy, or combinations of these. Guidelines should provide recommendations on the optimal management of a patient in specific clinical circumstances based on the scientific evidence. European Society for Medical Oncology（ESMO）Clinical Practice Guideline for Diagnosis, Treatment and Follow-up of Primary Breast Cancer (PBC)  is the only PBC recommendations on the optimal management of a patient in specific clinical circumstances based on the scientific evidence. Molecular testing and targeting therapy are the core contents of this guidelines updates in 2015 version.

Key words: guideline, primary breast cancer, surgery, chemotherapy, endocrine therapy

摘要：

在我国，乳腺癌已成为女性中最常见的恶性肿瘤且发病率增长迅速。原发性乳腺癌的治疗包括手术放疗等局部治疗，以及化疗、内分泌治疗，生物治疗等辅助综合治疗。临床指南是基于科学证据，同时对特定临床状况下的病人提出最佳治疗建议欧洲肿瘤内科学会（ESMO）《原发性乳腺癌诊断、治疗及随访指南》是惟一针对原发乳腺癌的临床指南。原发乳腺癌的分子检测与分子靶向治疗是该指南2015年更新的核心内容。

关键词: 指南, 原发性乳腺癌, 手术, 化疗, 内分泌治疗