Abstract:

Modified anterior approach to the inferior vena cava in large retroperitoneal liposarcoma：A report of 10 patients        QIU Hui，LI Cheng-peng，WU Jian-hui，et al. Sarcoma Center，Peking University Cancer Hospital &Institute；Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education)，Beijing 100142，China
Corresponding author：HAO Chun-yi，E-mail：haochunyi@vip.sina.com
Abstract    Objective    To explore the safety and feasibility of modified anterior approach to the inferior vena cava in large retroperitoneal liposarcoma. Methods    The clinical data of 10 patients performed extended resection with the modified anterior approach applied from August 2015 to February 2016 in Sarcoma Center of Peking University Cancer Hospital were analyzed retrospectively. Results    Totally complete resection and the modified anterior approach were successfully performed in all 10 patients, combined with 2 right hepatectomy, 6 pancreaticoduodenectomy, 10 right colectomy, 10 right nephrectomy and 2 partial resection and reconstruction of inferior vena cava. The R0 resection rate was 100%. The operation time and blood loss was 540-1000 min and 800-6000 mL respectively. One pancreatic fistula，two intra-abdominal abscess and one prosthetic vascular graft thrombosis were observed. One patient was treated operatively，and no patient died in hospital. Conclusion    Modified anterior approach is safe and feasible in resection of large retroperitoneal liposarcoma.

Key words: modified anterior approach, large retroperitoneal liposarcoma, multivisiceral resection

摘要：

目的    探讨改良下腔静脉前入路法在腹膜后脂肪肉瘤根治切除手术中应用的安全性和可行性。方法　回顾性分析北京大学肿瘤医院暨北京市肿瘤防治研究所软组织与腹膜后肿瘤中心2015年8月至2016年2月应用改良前入路法行肿瘤根治切除术治疗10例腹膜后巨大脂肪肉瘤病人的术中及术后资料。结果    10例病人均完整切除肿瘤。手术时间540～1000 min，术中出血800～6000 mL，联合右半肝切除2例，胰十二指肠切除术6例，右半结肠、右肾切除10例，下腔静脉切除重建5例。均达到R0切除，术后发生B级以上胰瘘1例，Clavien-DindoⅢ级以上腹腔感染2例，人工血管血栓形成1例，二次手术1例，无围手术期死亡。结论    应用改良前入路法切除右侧腹膜后巨大脂肪肉瘤安全、可行，值得开展进一步研究。

关键词: 改良前入路法, 巨大腹膜后脂肪肉瘤, 联合器官切除