关键词: 胰十二指肠切除术, 胰腺切除术, 消化道重建, 胰瘘

Abstract:

Risk factors of pancreatic fistula after pancreaticoduodenectomy        YANG Yin-mo.  Department of Surgery，Beijing University First Hospital，Beijing 100034，China  
Abstract    Pancreaticoduodenectomy offers the only chance of curative resection for periampullary tumors，which is technically challenging and is accompanied by a substantial risk for postoperative complications. The most significant complication is pancreatic fistula which often causes infectious complications，hemorrhage，which makes it the leading risk factor for postoperative death. Risk factors for development of pancreatic fistula are now well known，and several technical modifications，which focus on the type of pancreatic anastomosis，duct stenting，somatostatin and analogues，have been suggested in prevention of pancreatic fistula. Although no one technique of pancreatic anastomosis has been shown to be superior in decreasing the rate of pancreatic fistula，meticulous attention to intraoperative details by surgeons is necessary to prevent pancreatic fistula.

Key words: pancreaticoduodenectomy；pancreatectomy, digestive tract reconstruction；pancreatic fistula