中国实用外科杂志

• 专题笔谈 • 上一篇    下一篇

联合门静脉-肠系膜上静脉切除重建的腹腔镜胰十二指肠切除术关键技术环节

高    攀1,2,蔡云强1,彭    兵1   

  1. 1 四川大学华西医院胰腺外科,四川成都 610041;2 四川大学华西医院上锦医院  成都南府上锦医院肝胆胰微创中心,四川成都 611730
  • 出版日期:2022-05-01

  • Online:2022-05-01

摘要: 联合门静脉-肠系膜上静脉的胰十二指肠切除术可使部分血管侵犯病人可获得根治性手术机会并能从手术中获益。随着技术进步,联合门静脉-肠系膜上静脉切除重建的腹腔镜胰十二指肠切除术已在国内外少数中心开展,国内外多项回顾性研究结果证实该术式在围手术期是安全可行的。针对伴有肿瘤侵犯门静脉-肠系膜上静脉的腹腔镜胰十二指肠切除术,术前精准评估、合适的肠系膜上动脉入路、手术流程、合理的血管切除重建方式以及重建血管通畅性的术中评估是该技术的关键环节。由经验较为丰富的胰腺微创外科医师以及在较大的胰腺外科中心开展该技术能够大大提高该技术围手术期的安全性,该技术已从技术挑战阶段进入了更为规范合理的、以胰腺微创外科手术为主导的多学科综合治疗阶段。该技术对胰腺恶性肿瘤治疗的安全性与有效性,仍需要更多的随机、前瞻性的、大样本、多中心的高质量研究来证明。

关键词: 胰腺癌, 门静脉, 肠系膜上静脉, 腹腔镜胰十二指肠切除术, 血管切除

Abstract: Laparoscopic pancreaticoduodenectomy with venous resection and reconstruction: techniques and tips                        GAO Pan*, CAI Yun-qiang, PENG Bing. *Department of Pancreatic Surgery, West China Hospital, Sichuan University, Chengdu 610041, China; Department of Hepatobiliary and Pancreatic Minimally Invasive Surgery, Shangjin Nanfu Hosptial, Chengdu 611730, China
Corresponding author: PENG Bing,E-mail:pengbing84@hotmail.com
Abstract    Pancreaticoduodenectomy with venous resection and reconstruction makes the patients with venous invasion enable to get benefits from surgery. With the advancement of technology, Laparoscopic pancreaticoduodenectomy with venous resection and reconstruction develop rapidly and has been carried out in some centers. Some retrospective studies have confirmed that this operation is safe and feasible in the perioperative period. Accurate preoperative evaluation, superior mesenteric artery(SMA) approach, surgical procedure, reasonable vascular resection and reconstruction methods, and evaluation of the vascular patency are the tips of this technique. Experienced minimally invasive surgeons of high-volume centers can greatly improve the safety of this technique. The multidisciplinary approach affords the best hope for improved outcomes in patients with pancreatic cancer and the treatment for pancreatic cancer develops more reasonable and regulated. Further trials are needed to evaluate the role of neoadjuvant treatment and the application of the laparoscopic approach in patients with major venous who answered on treatment.

Key words: pancreatic cancer, portal vein, superior mesenteric vein, laparoscopic pancreaticoduodenectomy, vascular resection