腹膜后软组织肉瘤（RPS）复发或转移后的治疗非常棘手，对于无法获得根治性切除病人的姑息治疗尚有许多问题需要探讨。大多数RPS病人在他们疾病的进展过程中都将面临选择姑息治疗，手术、放疗和化疗是最常用的姑息治疗手段。一些病人通过合理的治疗后获得症状的缓解或生活质量的改善。当复发或转移的RPS选择进行姑息手术或放化疗时，应充分评估治疗的意义，平衡治疗获益及毒性反应。治疗肿瘤相关的疼痛、贫血、恶液质和短肠综合征同样具有重要的意义。

Palliative treatment of retroperitoneal sarcomas                         ZHOU Yu-hong*, LU Wei-qi. *Department of Medical Oncology, Zhongshan Hospital, Fudan University, Shanghai 200032, China
Corresponding author: LU Wei-qi, E-mail: luweiqi6@gmail.com
Abstract    The treatment of retroperitoneal sarcomas (RPS) with unresectable recurrent disease or metastatic disease is challenging. The role of palliative treatment is not well defined. Most of RPS patients will require a palliative treatment at some point. Surgery, radiotherapy, and chemotherapy are treatment options. Some patients have relief of their symptoms or improvement of their quality of life. Some end-stage patients need emotional and spiritual supports. The decision for palliative treatment should be based on optimizing the patients. The potential of treatment benefit and toxicity should be balanced and fully discussed with the patients and their families. Dealing with disease-related symptom such as pain, anemia, short bowel syndrome or cachexia has important significance.