药物是治疗消化道出血的基本措施。静脉曲张性上消化道出血主要选用生长抑素类或血管加压素类联合硝酸酯类药物；非静脉曲张性上消化道出血主要选用质子泵抑制剂。下消化道出血病因多样，药物的选用取决于病因。

Drug therapy of gastrointestinal bleeding        ZHAN Xian-bao. Department of Gastroenterology, Changhai Hospital, the Second Military Medical University, Shanghai 200433, China
Abstract    Drugs are the basic therapy of gastrointestinal bleeding. Somatostatin and its analogues, or vasopressin and its analogues combined with nitrates can be chosen for the management of esophagogastric variceal bleeding, while proton pump inhibitors are the first choice for treating nonvariceal upper gastrointestinal bleeding. The etiologies of lower gastrointestinal bleeding vary greatly, which determines the choice of drugs.