目的:总结分析甲状腺Hürthle细胞肿瘤诊治经验。方法:回顾性分析东南大学附属中大医院2002-2006年收治的15例甲状腺Hürthle细胞肿瘤的临床病理资料。结果:病人均以发现颈部包块就诊。女性14例。术前甲状腺功能检查均正常，B超、ECT 无法确诊，细针穿刺发现Hürthle 细胞。术中快速冰冻均能确诊。15例中，13例为良性，其中8例行腺叶切除加峡部切除，3例单纯腺叶切除，2例合并甲状腺乳头状癌而行根治术；2例为恶性，均行根治手术。术后随访无复发。结论:应充分认识甲状腺Hürthle 细胞肿瘤，重视细针穿刺细胞学检查。术中冰冻切片检查对诊断很重要。选择合适的手术方式可使病人获得良好的预后。

Objective:To summarize the experience of the diagnosis and treatment of thyroid Hürthle cell tumor. Methods:The clinical data of 15 cases of Hürthle cell tumor of thyroid gland admitted between 2002 and 2005 in the Affiliated ZhongDa Hospital of Southeast University were analyzed retrospectively. Results:Among 15 cases of Hürthle cell tumor of thyroid gland,14 cases were female.The most common symptom was solitary thyroid mass.The thyroid function test was normal.Untrasonography and ECT couldn't make a definite diagnosis.Hürthle cells were found by the fine needle aspiration cytology examination.Frozen section could give a definite diagnosis during operation.Thirteen cases were benign tumor.Among them,8 cases were performed total lobectomy and isthmusectomy,and 2 cases complicated with thyroid papillary tumor were performed lobectomy.Radical resection were performed for 2 cases of malignant tumor.There were no recurrence during followup peroid. Conclusion:It is important to be familiar with the entity.Frozen section analysis should be required during operation.Choosing appropriate resection method can get a good prognosis.