特殊部位胃肿瘤行双镜联合诊治要点

钱亚伟, 李圆, 杨力

中国实用外科杂志 ›› 2026, Vol. 46 ›› Issue (7) : 908-913.

PDF(5268 KB)
PDF(5268 KB)
中国实用外科杂志 ›› 2026, Vol. 46 ›› Issue (7) : 908-913. DOI: 10.19538/j.cjps.issn1005-2208.2026.07.10
专题笔谈·胃肿瘤的腹腔镜与内镜联合诊治

特殊部位胃肿瘤行双镜联合诊治要点

作者信息 +

Key points of laparoscopic and endoscopic cooperative surgery for the diagnosis and treatment of gastric tumors in special sites

Author information +
文章历史 +

摘要

双镜联合手术(LECS)的目的是在追求根治的同时最大限度保留胃的功能与病人生活质量。食管胃结合部、贲门、胃后壁、胃角及胃窦等特殊部位的胃肿瘤,因解剖结构复杂、毗邻关系特殊、操作空间受限,单纯内镜或腹腔镜手术均存在明显局限性。LECS通过整合内镜的腔内精准定位与腹腔镜下微创操作及缝合止血能力,在上述部位的治疗中具有独特优势,但其临床适用范围仍有明确边界。真正的挑战并非在于技术层面的可操作性,而在于能否为每一例病人制定个体化的治疗策略:有淋巴结转移风险时,应规范行淋巴结清扫;在无功能损害指征时,则应审慎控制切除范围,避免过度治疗。

Abstract

The aim of laparoscopic and endoscopic cooperative surgery (LECS) is to pursue radical resection while maximizing preservation of gastric function and the patient’s quality of life. For gastric tumors located in special sites—such as the esophagogastric junction, cardia, posterior gastric wall, gastric angle (incisura angularis), and antrum—the complex anatomy, special adjacent relationships, and limited operative space impose significant limitations on both pure endoscopic and pure laparoscopic approaches. LECS integrates the precise intraluminal localization of endoscopy with the minimally invasive manipulation and suturing/hemostatic capabilities of laparoscopy, thus offering unique advantages in treating tumors at these sites. However, its clinical indications remain clearly defined. The real challenge is not technical feasibility, but whether an individualized treatment strategy can be developed for each patient: when there is a risk of lymph node metastasis, standardized lymph node dissection should be performed; when there is no indication of functional compromise, the extent of resection should be carefully controlled to avoid overtreatment.

关键词

胃肿瘤 / 双镜联合手术 / 早期胃癌 / 胃间质瘤 / 功能保留

Key words

gastric tumor / laparoscopic and endoscopic cooperative surgery / early gastric cancer / gastic gastrointestinal stromal tumors / function preservation

引用本文

导出引用
钱亚伟, 李圆, 杨力. 特殊部位胃肿瘤行双镜联合诊治要点[J]. 中国实用外科杂志. 2026, 46(7): 908-913 https://doi.org/10.19538/j.cjps.issn1005-2208.2026.07.10
QIAN Ya-wei, LI Yuan, YANG Li. Key points of laparoscopic and endoscopic cooperative surgery for the diagnosis and treatment of gastric tumors in special sites[J]. Chinese Journal of Practical Surgery. 2026, 46(7): 908-913 https://doi.org/10.19538/j.cjps.issn1005-2208.2026.07.10
中图分类号: R6   

参考文献

[1]
Akahito S, Tomoyuki Y, Keiichi F, et al. Clinical epidemiology of the endoscopic, laparoscopic, and surgical resection of malignant gastric tumors in Japan, 2014-2021: A retrospective study using open data from a national claims database[J]. Gastric Cancer, 2025, 28(1): 1-11. DOI: 10.1007/s10120-024-01553-y.
[2]
Allemani C, Matsuda T, Carlo VD, et al. Global surveillance of trends in cancer survival 2000-14 (CONCORD-3): Analysis of individual records for 37 513 025 patients diagnosed with one of 18 cancers from 322 population-based registries in 71 countries[J]. Lancet, 2018, 391(10125): 1023-1075. DOI: 10.1016/S0140-6736(17)33326-3.
[3]
Shang L, Li ZY, Zhou PH, et al. 2024 Chinese expert consensus on clinical utilization of laparoscopic and endoscopic cooperative surgery for gastric tumors[J]. Chin Med J, 2025, 138(16): 1897-1903. DOI: 10.1097/CM9.0000000000003639.
[4]
Hiki N, Yamamoto Y, Fukunaga T, et al. Laparoscopic and endoscopic cooperative surgery for gastrointestinal stromal tumor dissection[J]. Surg Endosc, 2008, 22(7): 1729-1735. DOI: 10.1007/s00464-007-9696-8.
[5]
Hiki N, Nunobe S. Laparoscopic endoscopic cooperative surgery (LECS) for the gastrointestinal tract: updated indications[J]. Ann Gastroenterol Surg, 2019, 3(3): 239-246. DOI: 10.1002/ags3.12238.
[6]
J Korean Gastric Cancer Assoc. 2005-2006 Nationwide gastric submucosal tumor report in Korea[J]. J Gastric Cancer, 2008, 8(2): 104-109. DOI: 10.5230/jkgca.2008.8.2.104.
[7]
Niimi K, Ishibashi R, Mitsui T, et al. Laparoscopic and endoscopic cooperative surgery for gastrointestinal tumor[J]. Ann Transl Med, 2017, 5(8): 187. DOI: 10.21037/atm.2017.03.35.
[8]
段海涛, 梁品. 非暴露技术胃部分切除术治疗胃黏膜下层肿瘤的临床可行性分析[J]. 大连医科大学学报, 2024, 46(3): 217-220. DOI: 10.11724/jdmu.2024.03.05.
[9]
中国临床肿瘤学会指南工作委员会. 中国临床肿瘤学会(CSCO)胃肠间质瘤诊疗指南2026[M]. 北京: 人民卫生出版社, 2026.
[10]
Ismael H, Ragoza Y, Caccitolo J, et al. Optimal management of GIST tumors located near the gastroesophageal junction: case report and review of the literature[J]. Int J Surg Case Rep, 2016, 25: 91-96. DOI: 10.1016/j.ijscr.2016.06.008.
[11]
Abe N, Takeuchi H, Yanagida O, et al. Endoscopic full-thickness resection with laparoscopic assistance as hybrid NOTES for gastric submucosal tumor[J]. Surg Endosc, 2009, 23(8): 1908-1913. DOI: 10.1007/s00464-008-0317-y.
[12]
Goto O, Mitsui T, Fujishiro M, et al. New method of endoscopic full-thickness resection: A pilot study of non-exposed endoscopic wall-inversion surgery in an ex vivo porcine model[J]. Gastric Cancer, 2011, 14(2): 183-187. DOI: 10.1007/s10120-011-0040-y.
[13]
Kikuchi S, Nishizaki M, Kuroda S, et al. Nonexposure laparoscopic and endoscopic cooperative surgery (closed laparoscopic and endoscopic cooperative surgery) for gastric submucosal tumor[J]. Gastric Cancer, 2017, 20(3): 553-557. DOI: 10.1007/s10120-016-0641-6.
[14]
Inoue H, Ikeda H, Hosoya T, et al. Endoscopic mucosal resection, endoscopic submucosal dissection, and beyond: full-layer resection for gastric cancer with nonexposure technique (CLEAN-NET)[J]. Surg Oncol Clin N Am, 2012, 21(1): 129-140. DOI: 10.1016/j.soc.2011.09.009.
[15]
Kanehira E, Kamei Kanehira A, Tanida T, et al. CLEAN-NET: A modified laparoendoscopic wedge resection of the stomach to minimize the sacrifice of innocent gastric wall[J]. Surg Endosc, 2020, 34(1): 290-297. DOI: 10.1007/s00464-019-06766-w.
[16]
Hyung WJ, Lim JS, Cheong JH, et al. Laparoscopic resection of a huge intraluminal gastric submucosal tumor located in the anterior wall: eversion method[J]. J Surg Oncol, 2005, 89(2): 95-98. DOI: 10.1002/jso.20172.
[17]
Min JS, Seo KW, Jeong SH. Choice of LECS procedure for benign and malignant gastric tumors[J]. J Gastric Cancer, 2021, 21(2): 111-121. DOI: 10.5230/jgc.2021.21.e14.
[18]
Schlag C, Wilhelm D, von Delius S, et al. EndoResect study: endoscopic full-thickness resection of gastric subepithelial tumors[J]. Endoscopy, 2013, 45(1): 4-11. DOI: 10.1055/s-0032-1326017.
[19]
Shichijo S, Uedo N, Sawada A, et al. Endoscopic full-thickness resection for gastric submucosal tumors: Japanese multicenter prospective study[J]. Dig Endosc, 2024, 36(7): 811-821. DOI: 10.1111/den.14719.
[20]
Onimaru M, Inoue H, Ikeda H, et al. Combination of laparoscopic and endoscopic approaches for neoplasia with non-exposure technique (CLEAN-NET) for gastric submucosal tumors: updated advantages and limitations[J]. Ann Transl Med, 2019, 7(20): 582. DOI: 10.21037/atm.2019.09.22.
[21]
Goto O, Takeuchi H, Sasaki M, et al. Laparoscopy-assisted endoscopic full-thickness resection of gastric subepithelial tumors using a nonexposure technique[J]. Endoscopy, 2016, 48(11): 1010-1015. DOI: 10.1055/s-0042-111212.
[22]
消化系统疾病国家临床医学研究中心, 消化健康全国重点实验室, 中华医学会消化内镜学分会, 等. 早期胃癌双镜联合前哨淋巴结导航手术多学科临床诊疗实践专家共识(2026版)[J]. 中华消化内镜杂志, 2025, 42(12): 932-948. DOI: 10.3760/cma.j.cn321463-20251128-00507.
[23]
中国抗癌协会胃肠道间质瘤专业委员会, 中国抗癌协会胃癌专业委员会, 中华医学会消化内镜学分会经自然腔道内镜手术学组, 等. 中国胃肠道肿瘤双镜联合手术临床实践指南(2025,深圳)[J]. 消化肿瘤杂志(电子版), 2025, 17(3): 282-291. DOI: 10.3760/cma.j.cn441530-20241125-00381.
[24]
Abe N, Mori T, Takeuchi H, et al. Successful treatment of early stage gastric cancer by laparoscopy-assisted endoscopic full-thickness resection with lymphadenectomy[J]. Gastrointest Endosc, 2008, 68(6): 1220-1224. DOI: 10.1016/j.gie.2008.05.010.
[25]
邢继尧, 苗儒林, 吴齐, 等. 腹腔镜-内镜联合手术治疗早期胃癌初期病例技术分析[J]. 中国肿瘤临床, 2024, 51(13): 670-675. DOI: 10.12354/j.issn.1000-8179.2024.20240779.
[26]
Kim CG. Endoscopic full-thickness resection combined with laparoscopic surgery[J]. Clin Endosc, 2018, 51(1): 33-36. DOI: 10.5946/ce.2018.014.
[27]
Aizawa M, Yabusaki H, Matsuki A, et al. Intracorporeal hand-sewn anastomosis following pylorus-preserving gastrectomy: Surgical technique and short-term surgical outcome[J]. Langenbecks Arch Surg, 2022, 407(4): 1711-1720. DOI: 10.1007/s00423-022-02575-9.

脚注

利益冲突 所有作者均声明不存在利益冲突

基金

国家自然科学基金项目(81874219)
江苏省自然科学基金项目(BK20251953)

PDF(5268 KB)

Accesses

Citation

Detail

段落导航
相关文章

/