出凝血检测在排除诊断静脉血栓栓塞症（VTE）、辅助诊断易栓疾病、评估VTE危险度以及抗栓药物监测等方面有重要价值。临床医师在使用这些指标前，不但需充分考虑病人人群特点和药物影响，还应熟悉血栓试验的主要应用原则，包括：（1）在排除诊断VTE时，应了解本机构内D-二聚体方法的诊断敏感性，确保安全性和有效性。（2）D-二聚体应用于不同人群和诊疗目的时，相应的临界值可能不同。（3）对疑似遗传缺陷病人进行实验室筛查之前，应详细了解病史和家族史。（4）检测狼疮抗凝物、肝素诱导的血小板减少症抗体前，应首先使用相应的风险评估模型或验前概率评分筛选出符合检测指征的病人。

Value and clinic significance of detecting the hemostatic and coagulation function for the perioperaitive venous thromboembolism        MEN Jian-long. Tianjin Medical University General Hospital, Tianjin 300052,China
Abstract    There is the important value with hemostasis and coagulation function tests in excluding diagnosis of venous thromboembolism (VTE), assisting diagnosis with thrombophilia, estimating risk of VTE and antithrombotics monitoring. The clinician should consider fully about population characteristics and drug influence before implementing the tests, and should understand with the major application rules of thrombosis tests, including (1) excluding diagnosis of VTE, to understand the diagnostic sensitivity with the D-dimer in the medical institution and ensuring safety and effectiveness; (2) the clinician should use different cut-off values for different population and aim of diagnosis and treatment; (3) it should understand the medical history and family history detailed before laboratory screening for patients with suspected genetic defects; (4) it should use the risk assessment model and pre-test probability to screen the patients which accord with test indications before lupus anticoagulant and heparin-induced thrombocytopenia antibody test performance.