关键词: 口腔黏膜, 舌, 溃疡性嗜酸性肉芽肿

Abstract: Objective To study the clinicopathological features of the ulcerative eosinophilic granuloma of tongue（UEGT）and to know the disease deeply，prevent misdiagnosis，and to avoid excessive therapy. Methods The sections of five cases of UEGT were cut from paraffin-embedded blocks and stained with hematoxylin and eosin. Observe them under light microscope，and make analyses through combining with clinical manifestations and literature review. Results Clinically，this disease is characterized by the presence of small ulcerative lesions with elevated and indurated borders in the tongue. The tissue was infiltrated by many inflammatory cells，which were mainly eosinophils. The inflammatory cells could reach minor salivary glands and muscular layer. Sometimes，it might be mistaken for squamous cell carcinoma or malignant lymphoma. Conclusion This disease is a benign and self-limited disease. It can be cut partly or carried out local excision for biopsy. The trauma may be a very important factor for causes of the disease，and the pathogenesis is still unclear.

Key words: mouth mucosa, tongue, ulcerative eosinophilic granuloma