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02 February 2022, Volume 38 Issue 2 Previous Issue    Next Issue

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Study on the correlation between the heterogeneity of clinical presentation and pathogenesis of preeclampsia. WANG Yi-nan, LI Xiao-tian 2022, 38(2): 138-141.  DOI: 10.19538/j.fk2022020103 Abstract ( )   Due to the heterogeneity of pathogenesis，the clinical presentations of preeclampsia are highly complex. Based on the two key factors of pathogenesis of preeclampsia——fetal-placental factor and maternal factor，this study focused on the correlation between clinical heterogeneity and pathogenesis，in order to provide new ideas for making the individualized strategies of precise diagnosis and treatmen.

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To reduce stillbirth rate: pay attention to etiology analysis，screening and prevention. LIANG Jing-ying, CHEN Jing-si, CHEN Dun-jin 2022, 38(2): 141-145.  DOI: 10.19538/j.fk2022020104 Abstract ( )   With the progress of China's aging population and the opening of the "three-child policy"，it can be predicted that there will be an increase in advanced pregnancy，assisted reproduction and complications of pregnancy.The ratio of causes of stillbirth may change.It is of great significance to pay attention to the etiology analysis and screening of stillbirth and strengthen perinatal and maternal monitoring in order to reduce the stillbirth rate and ensure the safety of mothers and infants.

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HELLP syndrome without preeclampsia. HE Ying-dong, CHEN Qian 2022, 38(2): 145-149.  DOI: 10.19538/j.fk2022020105 Abstract ( )   The pathogenesis and clinical outcomes are different among early-onset HELLP syndrome，HELLP syndrome without preeclampsia and preeclampsia. Obstetricians should carefully identify the potential pathogenic factors to find the potential etiology of HELLP syndrome without preeclampsia in order to develop a reasonable treatment and improve maternal and fetal prognosis.

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Causes of preterm prelabor rupture of the membranes and the prevention and management.  ZHANG Qin-jian, YAN Jian-ying 2022, 38(2): 149-153.  DOI: 10.19538/j.fk2022020106 Abstract ( )   Preterm prelabor rupture of membranes（PPROM）is one of the obstetrical syndromes that seriously affect maternal and child health.It has a complex etiology with multiple pathways acting synergistically and causally with infection，and its management strategy has been extremely challenging. Management is currently based on the characteristics and prognosis of PPROM at different gestational ages，with emphasis on monitoring for signs of infection，and often requires a trade-off between progression of serious complications and risk of preterm delivery to determine the best time to terminate the pregnancy. However，due to the lack of understanding of the etiology，there is often a lag and passivity in diagnosis and treatment，and a more positive management strategy should focus on low-cost screening and interventions for different etiologies to help advance early prevention，control and refined management of PPROM.

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Thrombotic microangiopathy encountered in obstetrics. LAI Wei-si, DING Yi-ling 2022, 38(2): 153-157.  DOI: 10.19538/j.fk2022020107 Abstract ( )   Thrombotic microangiopathy is a syndrome characterized by microvascular embolism，which has acute onset，rapid progression，and a high mortality.Thrombotic microangiopathy rarely happens during pregnancy，so doctors are lack of awareness of this disease，which usually leads to missed diagnosis and misdisgnosis.This article summarizes the classification，pathogenesis，clinical manifestation，diagnostic criteria,differential diagnosis,therapy and prognosis of thrombotic microangiopathies.

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Whether an autoimmune disease is discovered in obstetrics department or first diagnosed during pregnancy. SONG Yi-jun, LIU Jun-tao 2022, 38(2): 157-161.  DOI: 10.19538/j.fk2022020108 Abstract ( )   Autoimmune diseases（AIDs） are not uncommon during pregnancy，and many are first diagnosed during pregnancy. It is an question worth discussing whether AID is a new occurrence or is first discovered during pregnancy. Since these AIDs can lead to some adverse pregnancy outcomes，how to identify these AIDs during pregnancy and give them approprate therapy early is essential to improving adverse pregnancy outcomes.

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Cause of secondary uterine contraction hemorrhage，joint treatment and DIC prevention and control. ZHANG Guo-hua, SHEN Xue-yan, CUI Wen-hua 2022, 38(2): 161-164.  DOI: 10.19538/j.fk2022020109 Abstract ( )   Postpartum haemorrhage remains the leading cause of maternal death worldwide.  During pregnancy and delivery，various reasons can lead to secondary uterine weakness，and improper treatment often leads to refractory postpartum hemorrhage，and even perinatal hysterectomy，disseminated intravascular hemorrhage（DIC），multiple organ failure and other serious complications.  Therefore，once postpartum hemorrhage occurs，it is necessary to find the cause in time, make joint treatment，accurately and effectively curb the development of the disease, and avoid the occurrence of severe postpartum hemorrhage and DIC caused by secondary uterine atnoy，which is the key to effectively reducing the mortality rate of postpartum hemorrhage in pregnant women.