Abstract: Autoimmune diseases（AIDs） are not uncommon during pregnancy，and many are first diagnosed during pregnancy. It is an question worth discussing whether AID is a new occurrence or is first discovered during pregnancy. Since these AIDs can lead to some adverse pregnancy outcomes，how to identify these AIDs during pregnancy and give them approprate therapy early is essential to improving adverse pregnancy outcomes.

Key words: autoimmune disease, antiphospholipid syndrome, systemic lupus erythematosus , adverse pregnancy outcomes

摘要： 自身免疫性疾病在妊娠期并不少见，很多是在妊娠期首次被确诊。这些妊娠期表现出来的自身免疫性疾病（autoimmune disease，AID）究竟是“新发生”，还是在妊娠期被首次发现，是一个值得探讨的问题。由于这些AID会导致一些不良妊娠结局，在妊娠期如何识别这些AID并及早给予相应处理，对改善不良妊娠结局至关重要。

关键词: 自身免疫性疾病, 抗磷脂综合征, 系统性红斑狼疮, 不良妊娠结局