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02 July 2020, Volume 36 Issue 7 Previous Issue    Next Issue

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Management of persistent high-risk HPV infection. ZHANG Yu-min，ZHANG Shi-qian 2020, 36(7): 588-592.  DOI: 10.19538/j.fk2020070104 Abstract ( )   Persistent high-risk human papilloma virus （HPV） infection is a necessary condition for cervical precancerous lesions and cervical cancer.However，the definition of persistent high-risk HPV infection is not uniform，which results in varying infection rate.Although guidelines for cervical cancer screening improve gradually，screening and management measures for persistent high-risk HPV infections have not been systematically discussed.As for patients with persistent high-risk HPV infections without histological lesions，it remains a problem whether it should be treated and how it should be treated in clinical practice.This article aims to search the published literature，reviewing the definition，infection rate，management measures and prevention of persistent high-risk HPV infections.

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Standardized colposcopy and the related precautions. KONG Dong-li，LI Shuang 2020, 36(7): 592-596.  DOI: 10.19538/j.fk2020070105 Abstract ( )   The purpose of standardized colposcopy is to improve the detection rate of HSIL + in the lower genital tract and perianal region，to guide the management of colposcopy biopsy，treatment and follow-up，and to minimize the damage.In clinical work，we should implement the colposcopy practical strategy based on the quantitative risk management，avoid the adverse factors for the colposcopy accuracy，and regularly evaluate and assess the colposcopy quality.It is essential to improve the colposcopy accuracy by the professional training of colposcopy doctors，the strict grasp of the indications of colposcopy，the improvement of medical history collection，the standardization of colposcopy procedure，the rationality of biopsy and ECC，et al.

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Clinicopathological significance of Silva pattern system in cervical adenocarcinoma and related research progress. WANG Wei，LIU Cong-rong 2020, 36(7): 596-601.  DOI: 10.19538/j.fk2020070106 Abstract ( )   Cervical adenocarcinoma is highly related to HPV infection，and Silva pattern system proposed recently can predict prognosis and guide clinical treatment better，compared with current clinical instruction.The diagnosis and treatment strategy of cervical adenocarcinoma，clinicopathological significance of Silva pattern system and related research progress were discussed in this article.

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Standardized management and follow-up of  cervical low-grade squamous intraepithelial lesion. CHEN Jing，LIU Mu-biao 2020, 36(7): 601-604.  DOI: 10.19538/j.fk2020070107 Abstract ( )   Low-grade cervical squamous intraepithelial lesion （LSIL） is a histological change secondary to acute HPV infection，with a good overall prognosis.Under the precondition of excluding more serious lesions，the management of LSIL is mainly follow-up.However，for LSIL with previous cytological results of ASC-H and HSIL，concealed HSIL should be excluded，and if necessary，diagnostic conization is recommended to reduce misdiagnosis.The individualized treatment for persistent or recurrent LSIL should be made after comprehensive evaluation.

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Standardized management and follow-up of cervical high-grade squamous intraepithelial lesion. GAO Shu-jun，SUI Long 2020, 36(7): 604-608.  DOI: 10.19538/j.fk2020070108 Abstract ( )   Cervical high-grade squamous intraepithelial lesions belong to preinvasive lesions，most of which are caused by high-risk HPV persistent infection.Cervical conization is the mainstream treatment nowadays.The region to be excised must be set strictly according to the guideline.Individual strategy should be adopted to manage those with postoperative positive margin.Management of young woman and pregnancy with HSIL should be conservative when invasive lesion is excluded.Long-term follow-up is recommended as the risk of invasive cervical cancer among these women is about five times greater than that among the general population of women.

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Recommendations for cervical cancer screening and management of cervical lesions in young women aged 21-24. ZHAO Jian，GUO Wen-wen 2020, 36(7): 608-612.  DOI: 10.19538/j.fk2020070109 Abstract ( )   The incidence of cervical cancer and precancerous lesions in 21-24-year-old young women is relatively low，and the possibility of reversion of cervical lesions is high in this age group.Therefore，it is recommended to use a separate cervical exfoliative cytology test for the primary screening of 21-24-year-old young women.For the abnormal cervical cytology screening results，follow-up check is recommended； the women with abnormal histopathology tend to be treated conservatively.According to the pathological grade and cytological screening results，the management is carried out in different levels，and cervical exfoliative cytology，high-risk HPV detection and colposcopy are used for follow-up check.

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Management of cervical lesion and HPV infection during pregnancy. YANG Ni，CHEN Fei 2020, 36(7): 612-615.  DOI: 10.19538/j.fk2020070110 Abstract ( )   In this review，we systematically described the epidemiology and natural history of cervical lesions，colposcopic indications，physiological changes of cervix and characteristics of colposcopic images， management principle of cervical lesions during pregnancy，and the epidemiology of HPV infection during pregnancy and its impact on pregnancy，outcome and delivery mode.

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Cervical cancer screening and management of cervical lesions in elderly women. LI Qiao，YIN Ru-tie 2020, 36(7): 615-617.  DOI: 10.19538/j.fk2020070111 Abstract ( )   Elderly women still have a higher risk of cervical cancer.However，due to a variety of factors，the cervical cancer screening is not enough and there is a lack of special guidance for screening and treatment of elderly women.In the current cervical cancer screening guidelines，there is a consensus that the elderly women who can not meet the screening conditions should continue to be screened due to the risk of disease.However，the suggestion that the 65 - year-old women who meet the criteria for stopping screening can't be screened is controversial.For the screening of cervical cancer and the treatment of cervical lesions in the elderly women，we should make full use of opportunistic screening，and take the particularity of the elderly women into full consideration when carrying out colposcopy and biopsy.For the elderly patients with obvious vaginitis，estrogen can be used locally two weeks before the examination； for those who are not satisfied with colposcopy，special exposure and biopsy techniques should be used.The author reviewed the literature and took advantage of her own experience，hoping to provide help for the screening of cervical cancer and the treatment for cervical lesions in elderly women.