Low-grade cervical squamous intraepithelial lesion （LSIL） is a histological change secondary to acute HPV infection，with a good overall prognosis.Under the precondition of excluding more serious lesions，the management of LSIL is mainly follow-up.However，for LSIL with previous cytological results of ASC-H and HSIL，concealed HSIL should be excluded，and if necessary，diagnostic conization is recommended to reduce misdiagnosis.The individualized treatment for persistent or recurrent LSIL should be made after comprehensive evaluation.