Abstract:

Abstract:With the progress in immunology，pregnancy complicated with autoimmune diseases (AID) is increasingly being found. The interaction exists between pregnancy and AID，and often associated with adverse pregnancy outcomes. So，how to identify the high-risk population or underlying AID patients before pregnancy，how to find the sick during pregnancy，and how to properly assess and manage the diagnosed patients to reduce the impact of AID to the mother and fetus，are the important issues that need obstetric and multidisciplinary common concern.

Key words: autoimmune disease, pregnancy, complications, clinical monitoring, autoantibody

摘要：

随着免疫学的进展，妊娠合并自身免疫性疾病(autoimmune disease，AID)越来越多地被发现。妊娠与AID之间的相互影响，往往与不良妊娠结局相联系。因此，如何在孕前识别高危人群或潜在发病者、如何在孕期发现患病者，以及如何对已确诊AID患者进行恰当的病情评估及管理，减少AID对母胎的影响，是产科及多学科共同关注和管理的重要问题。

关键词: 自身免疫性疾病, 妊娠, 并发症, 临床监测, 自身抗体