Abstract:

Malignant vaginal melanoma is a very rare malignant gynecological tumor associated with a poor prognosis due to high malignant degree，high metastatic rate and high recurrent rate.Surgical resection was the mainstay of primary therapy for early stage patients.Postoperative immunotherapy was appropriate option in high-risk patients.The multidisciplinary treatment was recommended for advanced stage patients.This review focuses on the literatures of case series，the latest researches and randomized clinical trials that led to change to the standards of care.

Key words: vagina, melanoma, diagnosis, management

摘要：

阴道恶性黑色素瘤是一种临床罕见的妇科恶性肿瘤，恶性程度高，复发、转移率高，预后差。早期患者首选手术治疗；高危患者需术后辅助免疫治疗。晚期患者采用综合治疗。文章结合近年研究进展及相关随机对照试验，探讨该病治疗的一些新变化。

关键词: 阴道, 黑色素瘤, 诊断, 治疗