中国实用妇科与产科杂志

中国实用妇科与产科杂志 ›› 2022, Vol. 38 ›› Issue (9): 881-885.DOI: 10.19538/j.fk2022090105

• 专题笔谈 • 上一篇    下一篇

子宫腔整复手术后再粘连的防治

  

  1. 温州医科大学附属第一医院妇科，浙江 温州 325000
  • 出版日期:2022-09-02 发布日期:2022-09-02
  • 通讯作者: 林凤
  • 基金资助:
    国家自然科学基金（81803781）

Prevention and treatment of re-adhesion after uterine cavity reconstruction surgery.

  1. Department of Gynecology,First Affiliated Hospital of Wenzhou Medical University,Wenzhou 325000，China
  • Online:2022-09-02 Published:2022-09-02

摘要： 宫腔粘连是子宫内膜基底层损伤所引起的疾病，严重影响女性生理健康和生育功能。宫腔镜下宫腔粘连分离术作为子宫腔整复手术的首选治疗方法，以恢复子宫正常解剖结构及功能为目的，但术后复发仍是妇科医生面临的巨大挑战。目前防治术后再粘连的方法主要有屏障治疗、激素治疗和羊膜疗法等，其他的治疗选择，如干细胞疗法、阿司匹林、富血小板血浆、西地那非等治疗尚处于研究当中。目前尚无防治术后再粘连的最佳治疗方案，如何达到最佳治疗效果仍需进一步研究。

关键词: 宫腔粘连, 宫腔粘连分离术, 复发, 防治策略

Abstract: Intrauterine adhesion occurs following the trauma in the basalt layer of uterine cavity，which not only influences the physical health of females but also damages fertility functions.With the expectation to restore the normal uterine anatomy and function，the first-choice treatment for intrauterine adhesion is hysteroscopic adhesiolysis，whereas the recurrence of adhesions is a great challenge.To date，prevention and treatment of the recurrence includes barrier therapy，hormonal therapy，and amniotic treatment.Other treatment options，such as stem cell therapy，aspirin，platelet-rich plasma，and sildenafil are still under study.It remains unclear which strategy is optimal，and further studies are needed to achieve the best effect.

Key words: intrauterine adhesion, hysteroscopic adhesiolysis, recurrence, prevention and treatment strategy

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