中国实用妇科与产科杂志

中国实用妇科与产科杂志 ›› 2022, Vol. 38 ›› Issue (5): 487-491.DOI: 10.19538/j.fk2022050103

• 专题笔谈 • 上一篇    下一篇

复发性外阴阴道假丝酵母菌病的预防与治疗

  

  1. 天津医科大学总医院妇产科 天津市女性生殖健康与优生重点实验室，天津 300052
  • 出版日期:2022-05-02 发布日期:2022-05-02
  • 通讯作者: 薛凤霞
  • 基金资助:
    国家自然科学基金（81471419，82101705）；天津市重大疾病防治科技重大专项（18ZXDBSY00200）；天津市医学重点学科（专科）建设项目（TJSYXZDXK020）

Prevention and treatment of recurrent vulvovaginal candidiasis. 

  1. Department of Obstetrics and Gynecology，Tianjin Key Laboratory of Female Reproductive Health and Eugenics，Tianjin Medical University General Hospital，Tianjin 300052，China
  • Online:2022-05-02 Published:2022-05-02

摘要： 复发性外阴阴道假丝酵母菌病（recurrent vulvovaginal candidiasis，RVVC）因反复发作难以根治，严重影响女性身心健康。做好RVVC预防，应寻找并纠正高危因素，鉴别感染的真菌菌种，认识混合感染。此外，研发抗真菌疫苗有望成为预防RVVC的新方法。RVVC治疗主要根据药敏试验采用敏感抗真菌药进行强化+巩固治疗，微生态调节剂、中成药等有一定的辅助治疗作用，未来有待开发新型抗真菌制剂并验证其临床疗效。

关键词: 复发性外阴阴道假丝酵母菌病, 预防, 治疗

Abstract: Recurrent vulvovaginal candidiasis （RVVC） is difficult to cure due to repeated attacks，which seriously affects women's physical and mental health. To prevent RVVC effectively，high-risk factors should be found and corrected，the fungal strains should be identified，and mixed infections should be recognized. Besides，the development of antifungal vaccines is expected to be a new approach to preventing RVVC. Antifungal induction and maintenance with selective drugs according to the drug susceptibility test is the main treatment. In addition，other treatments may have certain adjuvant therapeutic effects，including microecological regulators，Chinese patent medicine，etc. In the future，new antifungal preparations need to be developed and their clinical efficacy requires verification.

Key words: recurrent vulvovaginal candidiasis, prevention, treatment

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