中国实用妇科与产科杂志

中国实用妇科与产科杂志

• 专题笔谈 • 上一篇    下一篇

宫颈神经内分泌癌诊治困惑与对策

  

  1. 上海交通大学医学院附属仁济医院妇产科，上海 200080
  • 出版日期:2017-04-02 发布日期:2017-03-27
  • 通讯作者: 李卫平

Problems and countermeasures in the diagnosis and management of cervical neuroendocrine carcinoma

  1. Department of Obstetrics and Gynecology，Renji Hospital，Shanghai Jiao-Tong University，Shanghai 200080，China
  • Online:2017-04-02 Published:2017-03-27

摘要：

神经内分泌肿瘤占宫颈癌的1%～3% 。虽然罕见，但是一种较其他宫颈癌侵袭性更强的病理类型。至今，没有针对该疾病的前瞻性的研究来指导该疾病的诊断和治疗。美国妇科肿瘤学会（SGO）和国际妇科肿瘤协会（GCIG）基于现有的回顾性文献和专家经验发表了该疾病的诊治指南。目前的研究主要集中在进一步明确最佳治疗方案，明确肿瘤的分子机制以寻求新的治疗方法。文章目的在于复习文献，总结目前推荐的诊疗方法，建议可行的研究方向。

关键词: 宫颈神经内分泌癌, 诊断, 治疗

Abstract:

Neuroendocrine carcinoma of cervix is an aggressive，but rare，form of cervical cancer with an incidence of less than 3% of all cervical cancers.Nowadays，there are no prospective studies specific to this disease to guide the diagnosis and treatment.The Society of Gynecologic Oncology and Gynecologic Cancer Inter Group have issued consensus guidelines about the treatment for this disease based on the existing retrospective literature and expert opinion.Ongoing research is focused on further clarifying the best treatment regimen and defining molecular alterations of these tumors that can be exploited by novel treatment mechanisms.The objective of this manuscript is to review the literature，summarize current treatment recommendations，and propose possible research efforts for patients with neuroendocrine cervical cancer.

Key words: neuroendocrinal carcinoma of cervix, diagnosis, treatment

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