Abstract: Functional abdominal pain （FAP） is a common disease with abdominal pain as the main symptom in children，which seriously affects the children's quality of life. FAP is caused mainly by changes in brain-gut axis，resulting in gastrointestinal barrier dysfunction，disturbed gastrointestinal motility，visceral hypersensitivity，intestinal dysbacteriosis and so on. Probiotics， as an important means of non-drug treatment，has obvious effect in the treatment of FAP. This article reviews the mechanism of probiotics in the treatment of FAP in children.

Key words: functional abdominal pain, probiotics, child

摘要： 功能性腹痛（functional abdominal pain，FAP）是儿童常见的以腹痛为主要症状的疾病，严重影响着患儿的生活质量。儿童FAP的发病机制主要有脑-肠轴改变引起的胃肠道屏障功能受损、胃肠动力异常、内脏高敏感性、肠道菌群失调等多种因素。益生菌作为非药物治疗的重要手段对治疗儿童FAP有明显疗效。该文对益生菌治疗儿童FAP的作用机制进行阐述。

关键词: 功能性腹痛, 益生菌, 儿童