Abstract: Objective    To explore the clinical characteristics of chidren with foreign bodies in the upper gastrointestinal tract，and to investigate the influencing factors of complications and endoscopic removal failure. Methods    Data of 756 cases of children with foreign bodies in upper gastrointestinal tract were collected retrospectively at the Second Affiliated Hospital of Wenzhou Medical University from January 2015 to February 2020.Gender，age，the location and duration of foreign body ingestion and the types of foreign bodies were analyzed to study their influence on occurrence of complications and endoscopic removal failure. Results    A total of 756 cases（468 males and 288 females）were enrolled. The median age was 3 years，with peak age being 1-3 years（57.9%）. About 1.1% of patients had esophageal diseases. The most common foreign body ingested was coin（n=543，71.8%）. Foreign bodies were most commonly located in the entrance of esophagus（n=376，49.7%）.The duration of foreign body ingestion ranged from 1 hour to 1 month. There were 7.8% of children who developed complications. Long time of foreign body ingestion， esophageal foreign body and sharp foreign body were risk factors of complications（P<0.05）. The success rate of endoscopic removal of foreign body was 96.3% The influencing factors of endoscopic foreign body removal had no influence on the result of operation（P>0.05）. Conclusion    Coin is the most common foreign body in upper gastrointestinal tract in childhood.Foreign bodies are most commonly located in the entrance of esophagus.Endoscopic removal of foreign bodies from the upper gastrointestinal tract in children has a high success rate. Long time of foreign body ingestion， esophageal foreign body and sharp foreign body increase the risk of complications.

Key words: gastrointestinal tract, foreign bodies, child, endoscopy

摘要： 目的    探讨儿童上消化道异物病例临床特点，并分析并发症发生和胃镜治疗成败的影响因素。方法    总结2015年1月至2020年2月温州医科大学附属第二医院收治的经电子胃镜确诊的756例儿童上消化道异物病例资料，分析不同性别、年龄、嵌顿部位、嵌顿时间、异物性质等对并发症的发生和胃镜治疗成败的影响。结果    756例患儿中男468例（61.9%），女288例（38.1%）；中位年龄3岁，其中1～3岁最为多见（57.9%）；其中1.1%的患儿合并食管基础疾病。异物以硬币最为常见（71.8%，543/756），多嵌顿于食管入口（49.7%，376/756），嵌顿时间1 h至1个月。异物嵌顿并发症发生率为7.8%，嵌顿时间长、食管嵌顿、锐性异物是并发症发生的危险因素（P<0.05）。经胃镜上消化道异物取出术成功率为96.3%。儿童内镜下上消化道异物取出术各影响因素对手术成败差异均无统计学意义（P>0.05）. 结论    儿童上消化道异物以硬币多见，常嵌顿于食管入口。经胃镜上消化道异物取出术成功率高，嵌顿时间长、食管嵌顿及锐性异物可增加异物嵌顿并发症发生的风险。

关键词: 消化道, 异物, 儿童, 消化内镜