中国实用儿科杂志

中国实用儿科杂志 ›› 2021, Vol. 36 ›› Issue (11): 839-842.DOI: 10.19538/j.ek2021110608

• 党为人民谋健康的 100 年·专题笔谈 • 上一篇    下一篇

幼年皮肌炎慢作用药物治疗进展

  

  1. 1.天津市儿童医院（天津大学儿童医院）综合内科（免疫），天津  300074；2. 天津医科大学研究生院，天津  300070
  • 出版日期:2021-11-06 发布日期:2022-01-04
  • 通讯作者: 胡坚，电子信箱：h1957_7591@126.com

Advances of slow- acting antirheumatic drug for juvenile dermatomyositis

  1. *Department of General Medicine（Immunology），Tianjin Children’ s Hospital（Children’s Hospital of Tianjin University），Tianjin  300074，China
  • Online:2021-11-06 Published:2022-01-04

摘要： 幼年皮肌炎是儿童少见的风湿性疾病之一，常用的治疗方案是激素联合慢作用药物。由于发病率较低，缺少大样本随机对照试验研究，选择哪种慢作用药物、了解药物之间的转换以及确定疗程是比较困难的。该文对治疗幼年皮肌炎的常用慢作用药物及其作用机制、剂量、不良反应和适应证进行介绍，有助于临床医师对药物选择进行权衡。

关键词: 幼年皮肌炎, 慢作用抗风湿药物, 治疗

Abstract: Juvenile dermatomyositis is one of the rare rheumatic diseases in children. The common treatment is hormone combined with slow-acting drugs. It is difficult to choose slow-acting drugs，swith drugs and design course of treatment because of the low incidence and lack of large randomized controlled trials. The author summarizes the common slow-acting antirheumatic drugs used in the treatment of juvenile dermatomyositis，and introduces the mechanism of action，dosage，adverse reactions and indications of these drugs，in order to help doctors to select drugs.

Key words: juvenile dermatomyositis, slow- acting antirheumatic drug, treatment