Abstract: The incidence of autoimmune hepatitis in children is lower than in adults，but the liver of children is more susceptible to damage caused by factors such as infections or drugs，making it more difficult to diagnose.The impact on growth and development needs to be considered during the period of long-term immunosuppressive therapy，and there is more uncertainty.This paper refers to the latest relevant guidelines，and through combination with clinical practice，it discusses the difficulties in the diagnosis and treatment of childrens AIH，and puts forward relevant suggestions.

Key words: autoimmune hepatitis, infection, drug, child

摘要： 儿童自身免疫性肝炎（AIH）发病率低于成人，但儿童肝脏更易受到感染或药物等因素所致损伤，使其诊断更加困难，在长期免疫抑制治疗中需考虑对其生长发育的影响，存在更多不确定性。文章参照最新国内外相关指南，结合临床实践，讨论儿童AIH诊断和治疗过程中的难点问题，并提出相关思考或建议。

关键词: 自身免疫性肝炎, 感染, 药物, 儿童