Abstract: Present status and progress of clinical liver transplantation for hepatocellular carcinoma        ZHOU Jian，XIAO Yong-sheng. Department of Liver Surgery and Transplantation，Liver Cancer Institute, Zhongshan Hospital, Fudan University，Shanghai  200032，China
Corresponding author：ZHOU Jian，E-mail：zhou.jian@zs-hospital.sh.cn
Abstract    Liver transplantation has become a curative treatment for hepatocellular carcinoma，however，postoperative recurrence and metastasis seriously limit its efficacy improvement. In recent years，domestic and foreign scholars have carried out a large number of studies on recurrence of liver transplantation. In this paper，we reviewed and prospected the progress of clinical  on liver transplantation from the perspectives of screening liver transplantation recipients，preoperative neoadjuvant/down-stage treatment，and comprehensive prevention and treatment for posttransplant recurrence and metastasis.

Key words: hepatocellular carcinoma, liver transplantation, recurrence and metastasis, neoadjuvant therapy, immune inhibition, comprehensive treatment

摘要： 肝移植已经成为肝细胞癌根治性治疗的重要手段，但术后复发转移严重限制了其疗效的进一步提升。近年来，国内外学者围绕肝移植术后复发开展了大量研究。本文从肝癌肝移植受体的筛选、术前新辅助/降期治疗以及术后复发转移的综合防治3个角度，对肝癌肝移植临床研究进展进行综述与展望。

关键词: 肝细胞癌, 肝移植, 复发转移, 新辅助治疗, 免疫抑制, 综合治疗