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  • Online:2018-10-01 Published:2018-10-10

直肠癌预防性侧方淋巴结清扫的价值

叶颖江申占龙,王    搏   

  1. 北京大学人民医院胃肠外科 外科肿瘤研究室 结直肠癌诊疗研究北京市重点实验室,北京 100044

Abstract:

Value of prophylactic lateral lymph node dissection in rectal cancer        YE Ying-jiang,SHEN Zhan-long,WANG Bo. Department of Gastroenterological Surgery,Laboratory of Surgical Oncology,Beijing Key Laboratory of Colorectal Cancer Diagnosis and Treatment Research,Peking University People's Hospital,Beijing 100044,China
Corresponding auhor:YE Ying-jiang,E-mail:yeyingjiang@
pkuph.edu.cn
Abstract    The lymph nodes dissection manner and range are dependent on the special characteristic of lymphatic drainage of rectum. However,lateral lymph node dissection (LLND) for low rectal cancer is still a controversial issue. Lateral lymph node dissection might decrease local recurrence of patients with rectal cancer, but with increasing risk for operation-related complications and uncertainty in improving long-term survival. Combined with preoperative imaging evaluation and sufficiently multidisciplinary discussion, plus an appropriate surgical indication, prophylactic lateral lymph node dissection still has a broad space for application.

Key words: rectal cancer, lateral lymph node dissection, prophylactic, recurrence, complication

摘要:

直肠特殊的淋巴引流特点决定了直肠癌侧方淋巴结清扫(LLND)的范围和方式。对于低位直肠癌是否应行预防性LLND目前仍存在较大分歧和争议。LLND可能降低直肠癌局部复发率,但同时也增加了相关手术并发症的发生风险,且对远期生存的改善仍不确定。结合术前影像学评估和充分的多学科讨论,把握好LLND的指征,预防性LLND仍有其广阔的应用空间。

关键词: 直肠癌, 侧方淋巴结清扫, 预防性, 复发, 并发症