Abstract:

Surgical treatment of pancreatic metastases from renal cell carcinoma : A report of 3 cases        LIN Xian-chao, HUANG He-guang, CHEN Yan-chang, et al.Department of General Surgery, Fujian Medical University Union Hospital, Fuzhou 350001, China
Corresponding author: HUANG He-guang, E-mail: heguanghuang2@163.com
Abstract    Objective    To investigate the value of surgery in the management of pancreatic metastases from renal cell carcinoma（PMRCC）.Methods    The clinical data of 3 patients with PMRCC who underwent pancreatectomy in Fujian Medical University Union Hospital between October 2010 and April 2018 were reviewed，including general information，accessary examination，perioperative data and follow-up status. Results    Of the 3 patients，2 patients had multiple lesions of the pancreas and the other one had a single lesion of pancreas. All of the 3 cases were asymptomatic. Primary cancer was renal clear cell cancer in all of them and the mean time from resection of the primary tumor to pancreatic metastases was 7 years （range 3-15 years）. Two patients underwent laparoscopic distal pancreatectomy with splenectomy and 1 underwent total pancreatectomy. Intra-abdominal infection was observed in 2 patients after pancreatic surgery and no pancreatic fistula occurred.Postoperative pathological diagnosis was metastatic renal cell carcinoma in all of the 3 patients. One patient died at 22 months after the pancreatic surgery and the other 2 patients were disease free with a follow-up of 15 and 39 months respectively. Conclusion    The prognosis of PMRCC is good. Surgical treatment is suitable for isolated PMRCC, especially for the metastases in the body and tail of pancreas.

Key words: pancreatic metastases, renal cell carcinoma

摘要：

目的    探讨手术治疗胰腺转移性肾细胞癌（PMRCC）的价值。方法    回顾性分析2010年10月至2018年4月福建医科大学附属协和医院3例手术PMRCC病人的临床资料，包括一般资料、临床表现、辅助检查、手术情况、术后随访情况等。结果    3例PMRCC，2例肿瘤为多发，1例肿瘤为单发。3例病人均无临床症状，原发肿瘤均为肾透明细胞癌，胰腺转移距肾癌手术时间间隔为3～15年，平均7年。2例行腹腔镜胰体尾+脾切除术，1例行全胰十二指肠切除术。3例均无胰瘘，2例术后并发腹腔感染。术后病理学检查结果均为胰腺转移性透明细胞癌。1例病人胰腺术后生存时间为22个月，另2例分别随访15个月及39个月仍无瘤生存。结论    PMRCC总体预后较好，手术治疗适用于孤立性PMRCC，尤其是胰体尾病例。

关键词: 胰腺转移癌, 肾细胞癌