Abstract:

Reasonable option of crystal solution in the fluid therapy           AN You-zhong，ZHAO Hui-ying. Department of Intensive Care Unit，Peking University People’s Hospital，Beijing 100044，China
Corresponding author：AN You-zhong，E-mail：bjicu@163.com
Abstract    A single ideal “universal” liquid for treatment is not exist. According to different etiology and pathophysiological conditions， liquid for treatment should be selected individually. Artificial colloid fluid infusion can cause organ damage. Because its artificial solute component is difficult to be metabolized rapidly and completely，and phagocytized. So its application has been reduced greatly and must be used carefully. It is emphasized progressively that crystal solution is similar to the composition of extracellular fluid (plasma). Normal saline can usually cause disorder of acid-base balance and electrolyte and kidney damage by chloride ion containing high. Balanced salt solution as a continued focus of clinical attention is used widely. For patients with the liver and kidney dysfunction and lactic acidosis，acetate balanced salt solution is better than lactated Ringer’s solution.

Key words: balanced salt solution；normal saline；lactated Ringer&rsquo, s solution；acetate balanced solution

摘要：

单一理想的“万能”治疗液体并不存在，针对不同病因与不同病理生理状态应该个体化地选择相应的治疗液体。人工胶体液大量输注时由于其溶质成分难以被机体迅速完全代谢及吞噬清除而沉积于组织造成器官损害，应用已大为减少且须慎重；晶体液的选择也日益强调应尽可能与细胞外液（血浆）的成分类似。生理盐水因含过高的氯离子而易造成酸碱平衡和电解质紊乱以及肾脏损伤；平衡盐溶液正日益受到临床重视而扩大其应用，其中对于肝肾功能不全和乳酸酸中毒的病人，醋酸平衡盐溶液优于乳酸林格液。

关键词: 平衡盐溶液, 生理盐水, 乳酸林格液, 醋酸平衡盐溶液