Totally laparoscopic distal gastrectomy and laparoscopic-assisted distal gastrectomy：A Meta-analysis of efficacy comparation        WANG Jun-fu, XIE Yong,  HU Lin, et al. Department of Gastrointestinal Surgery, the Second Affiliated Hospital of Nanchang University, Nanchang330006, China
Corresponding author: LI Hong-lang, E-mail: lihonglang6802@163.com
Abstract    Objective    To compare the effect difference of totally laparoscopic distal gastrectomy（TLDG） and laparoscopic-assisted distal gastrectomy （LADG）. Methods    Randomized controlled trial reports on TLDG and LADG from 2008 to 2013 were collected from PubMed，EMBASE，Medline，China National Knowledge Infrastructure (CNKI) and Wanfang databases. RevMan 5.1 software was used for data analysis. Results    According to the included criteria, 6 clinical trials were selected finally. Meta-analysis showed that: blood loss in TLDG group was 31.26mL less than that in LADG group (P=0.005); The frequency of analgesic usage in the TLDG group was 0.38 times lower than LADG group (P=0.04); serum C-reactive protein levels decreased 0.93g/L after one day in TLDG group (P=0.03). There was no statistical difference in operation time, hospital stay, postoperative first exhaust time and complications between the two groups（P＞0.05）. Conclusion    It could not demonstrate the clinical superiority of TLDG over LADG based on the current data. The surgical method may be selected according to patients’ conditions and the surgeon’s preference.